The Artemis II astronauts are now more than halfway to the moon, preparing for a historic lunar fly-around to break Apollo 13's distance record.
However, their toilet has been malfunctioning since liftoff, with engineers suspecting ice may be blocking the line that prevents urine from flushing overboard.
Astronauts Victor Glover, Debbie Korth, and Mission Control have instructed the crew to use backup urine collection bags until the issue is resolved.
The crew, consisting of three Americans and one Canadian, is set to reach the moon on Monday and photograph the lunar far side.
This mission marks the first moon-bound crew in over 53 years, aiming to set a distance record of over 252,000 miles from Earth.
The Artemis II mission is a crucial step towards establishing a sustainable moon base, with NASA planning to land two astronauts near the lunar south pole in 2028.