The Israeli army has struck Iran's 'Taleghan' compound, a site it claimed was used by the Iranian regime to advance nuclear weapons capabilities.
Iran launched a series of attacks across the Gulf, striking a container ship off Dubai, triggering a blaze near Bahrain’s international airport and targeting a major Saudi oil field with a drone.
The strikes came despite a U.N. Security Council resolution passed a day earlier demanding that Tehran stop attacks on its Gulf neighbours.
New attacks were also reported in Kuwait and the United Arab Emirates.
In Israel, sirens sounded before dawn in Jerusalem as the military intercepted incoming Iranian missiles.
Loud explosions were heard later in the day as the city came under another round of attack.
The US-Israeli conflict with Iran entered its 13th day on Thursday, with attacks on vessels in the Strait of Hormuz raising fresh concerns over global oil supplies.
The Trump administration plans to release 172 million barrels from the US emergency oil reserve as part of a coordinated effort by countries around the world to ease surging crude and fuel prices.