At least 200 American soldiers were killed and over 3,000 were wounded within the first week of the Iran-US war, according to an Iranian official cited by Press TV.
The official claimed that the US lost 150 missile launch platforms, 23 patriot air defence systems, and 37 aircraft and helicopters were destroyed.
The official also said that 43% of Washington's arms stock has been wiped out, describing the situation as "very serious".
US President Donald Trump has made similar claims, saying Iran was nearly obliterated in the US military action.
The US has stepped up its attacks on Iran, dropping 5,000-pound buster bombs targeting sites along Iran's coastline near the Strait of Hormuz.