Israel launched a new wave of strikes on Tehran and Hezbollah command centers in Beirut, while Iran fired more missiles toward Israel and struck Azerbaijan, the 13th nation to be attacked since the start of the war.
The Israeli military targeted civilian locations used by Iranian security forces in emergency situations, including several sports venues in Tehran.
The U.S. military has sunk or destroyed over 30 Iranian warships, including a large drone carrier, said Admiral Brad Cooper, commander of U.S. Central Command.
The conflict has forced a de facto closure of the Strait of Hormuz, trapping ships in the Persian Gulf while forcing Gulf oil producers to slash output and Asian refiners to hunt for alternative supplies.
Foreign ministers of the Arab League member states will hold an emergency meeting Sunday to discuss Iran's attacks on several countries in the region.
NATO has strengthened its ballistic-missile defenses across the alliance, and the State Department has closed the U.S. Embassy in Kuwait.