Oprah Winfrey has sparked concerns about her health and weight loss after being spotted at the Paris Fashion Week Chloé show.
Videos of the 72-year-old talk show host with longtime friend Gayle King quickly went viral online, with several people expressing concerns about her health.
A person who shared the video asked, 'What in the Ozempic Oprah is going on here?' and another added, 'I'm afraid Oprah may OD on Ozempic. Welfare check, please!'
Oprah has confirmed that she takes weight loss medication, but never specified if it is Ozempic, a particular brand.
She had said in a January 2025 podcast episode that she took a GLP-1 agonist, which could include brand names like Ozempic.
GLP-1 class of drugs work by mimicking the GLP-1 hormone, which the body releases after eating, making people feel full and slowing stomach emptying.